Immunomodulation, Bioavailability and Safety of Bacteriocins

نویسندگان

چکیده

The rise of antibiotic-resistant bacteria and the emergence new pathogens have created a need for strategies to fight against infectious diseases. One promising approach is use antimicrobial peptides produced by certain species bacteria, known as bacteriocins, which are active other strains same or related species. Bacteriocins can help in treatment prevention Moreover, bacteriocins be obtained prokaryotic organisms, contribute s their widespread use. While currently limited food industry (for example, nisin used preservative, E234), large number studies on microbicidal properties suggest that medicine may increase foreseeable future. However, successful medicine, it necessary understand effect immune system, especially cases where immunity weakened due processes, oncological, allergic, autoimmune Studies immuno-modulatory activity animal models human cells revealed ability induce both pro-inflammatory anti-inflammatory factors involved implementation innate immunity. influence acquired an T-lymphocytes with simultaneous decrease B-lymphocyte levels, makes them attractive substances reducing inflammation. industry, low toxicity, broad narrow specificity reasons researchers pay attention immunomodulatory explore medical applications. Inflammation regulation various pathologies. aim review was analyze scientific publications activity, bioavailability, safety order data organize preclinical clinical studies.

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ژورنال

عنوان ژورنال: Life

سال: 2023

ISSN: ['2075-1729']

DOI: https://doi.org/10.3390/life13071521